The most prevalent causes of Outlook crashing problems are explained below. Corrupted PST File - The usual behavior of the PST file might be the cause of the Outlook crashing issue. MS Outlook profile corruption - Occasionally, the MS Outlook profile becomes corrupt, causing the program to crash. Corrupted Configuration File - A corrupted Configuration file may cause Outlook to crash. Emails that do not include genuine attachments might potentially harm the MS Outlook program.