there is far too much open space to say it doesn't support an optical drive. it may not have a bracket for it, but that is easy to overcome. I have mine sitting flat, and used the pedestal shown for a water reservoir to mount a blue ray player. used a couple of the covers I removed for the back of the expansion slots to support the other side. ultimately, I will pull the 5.25" cage from my old case and mount it inside this one. there I'd ample room to okay with, especially if you mount your drives behind the mobo. since I'm running 3 SSD and no HDD, heat isn't an issue, so they're safely out of the way. as long s you aren't running 480mm radiator, there are several options to mount 1 or more drives along that front face.
hope this helps