Sorry to dreg up an old thread but it's the first to pop on on google and has no real answer. From what i am finding TT RGB locks itself to the first audio device it sees you on so if you switch to headphones it doesn't switch with it. Easy fix check volume mixer and see where your TT RGB Plus sound is at (this is how it gets its sound data). If it's not on the output you are using exit TT RGB and open it while on the sound output you want. I have tested this with several different outputs and have had success so far. Hope this helps someone down the line.